Thoracic Oncology Laboratory »  Alumni »  Postdoctoral Fellows »  Li Tai Fang, Ph.D.
Li Tai Fang, Ph.D.

Li Tai Fang, Ph.D.

Postdoctoral Fellow (Bioinformatics)

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  • 2010, Ph.D., Biochemistry, UCLA
  • 2003, B.A., Molecular Biology, UC Berkeley
  • 2011 - 2014, UCSF Medical Center
  • 2010, Fritz Haber Center for Molecular Dynamics, Hebrew University of Jerusalem, Israel
  • Bioinformatics and Biostatistics
  • Develop tools in Python and MATLAB
  • Next Generation Sequencing (NGS) and Microarray Gene Expression

Li Tai was a bioinformaticist from 2011 to 2014. He focused primarily in the bioinformatics analysis of micoarray gene expression and Next Generation Sequencing (NGS) data. He is currently a Bioinformatics Scientist at Bina Technologies, Inc

Prior to UCSF, Li Tai has completed a 6-month theoretical chemistry fellowship with Professor Avinoam Ben-Shaul in the Hebrew University of Jerusalem. They have together developed a simple mathematical model to approximate the 3D size of single-stranded RNA molecules. 

Li Tai has also obtained a Ph.D. in Biochemistry from the UCLA in 2010, having worked with Professors William M. Gelbart and Charles M. Knobler. His dissertation is the Physics of DNA, RNA, and RNA-like Polymers. Li Tai's work on the mathematical model of RNA has won him UCLA's George Gregory Research Award in Physical Chemistry in 2009.

He also has a B.A. in Biochemistry from UC Berkeley in 2003.

I have developed a number of Internal Programs for microarray and Next Generation Sequencing (NGS) analysis. We are equipped with Life Technologies SOLiD 5500, Ion ProtonIon Torrent, and 3730 DNA Analyzer

Microarray analysis programs are mainly written in MATLAB and Python 3 for data exported by Affymetrix GeneTitan. For NGS, some internal programs are developed to further process the analysis and annotations generated by LifeScope Genomic Analysis SoftwareANNOVAR, Strelka, MuTect, Samtools, Picard, etc. 

  1. Li Tai Fang, Sharon Lee, Helen Choi, Hong Kwan Kim, Gregory Jew, Hio Chung Kang, Lin Chen, David Jablons, and Il-Jin Kim. Comprehensive Genomic Analysis of a Metastatic Colon Cancer to the Lung by Whole Exome Sequencing and Gene Expression AnalysisInternational Journal of Oncology, 44(1): 211-221. (2014)
  2. Michael Mulvihill, Yong-Won Kwon, Sharon Lee, Li Tai Fang, Helen Choi, Roshni Ray, Hio Chung Kang, Jian-Hua Mao, David Jablons, and Il-Jin Kim. Gremlin is Overexpressed in Lung Adenocarcinoma and Increases Cell Growth and Proliferation in Normal Lung Cells. PLoS ONE, 7(8): e42264. (2012)
  3. James Wan Soo Kim, Sharon Lee, Natalie Lui, Helen Choi, Michael Mulvihill, Li Tai Fang, Hio Chung Kang, Yong-Won Kwon, David Jablons, and Il-Jin Kim. A Somatic TSHR Mutation in a Patient with Lung Adenocarcinoma with Bronchioloalveolar Carcinoma, Coronary Artery Disease and Severe Chronic Obstructive Pulmonary Disease. Oncology Reports, 28(4): 1225-1230. (2012)
  4. Li Tai Fang, William M. Gelbart, and Avinoam Ben-Shaul. The Size of RNA as an Ideal Branched Polymer. Journal of Chemical Physics, 135(15): 155105. (2011)
  5. Li Tai Fang. The End-to-End Distance of RNA as a Randomly Self-Paired Polymer. Journal of Theoretical Biology, 280: 101-107. (2011)
  6. Li Tai Fang, Aron M. Yoffe, William M. Gelbart, and Avinoam Ben-Shaul. A Sequential Folding Model Predicts Length-Independent Secondary Structure Properties of Long ssRNA. Journal of Physical Chemistry B, 115(12): 3193-3199. (2011)

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