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Yi-Lin Yang, Ph.D.

Yi-Lin Yang, Ph.D.

Assistant Specialist

Contact Information

Thoracic Oncology Laboratory
UCSF Helen Diller Family Comprehensive Cancer Center
2340 Sutter St, Room N261
San Francisco, CA 94143-1724
(415) 502-2555
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  • Kaohsiung Medical University, B.A., Biology, 2001
  • Oregon Health & Science University, M.S., Biochemistry and Molecular Biology, 2004
  • Tufts University, Ph.D., Comparative Biomedical Sciences, 2010
  • Postdoctoral Fellow, San Francisco VA Medical Center, San Francisco, 2010-2012
  • Biomarker for early diagnosis
  • Lung cancer and mesothelioma
  • Molecular therapy development
  • Post-translational modification
  • Transgenic mouse models

Yi-Lin joined the Thoracic Oncology Laboratory at the UCSF in 2012. She uses in vivo and in vitro models to study the biological mechanisms in the development of lung cancer and mesothelioma, and her research focuses on finding the therapeutic targets to the diseases.

Prior to joining the team, Yi-Lin received her Ph.D. degree in Comparative Biomedical Sciences from Tufts University in 2010. While working with Dr. Giovanni Widmer in Tufts University, she obtained the transcriptional profiles in human cells and identified potential biomarkers specific to pathogen infection. In addition to biomarker, she is also interested in therapeutic discovery. After graduation, Yi-Lin worked with Dr. Michael Mann as a postdoctoral fellow and focused on developing molecular therapies for cardiothoracic disorders in San Francisco VA Medical Center.

Yi-Lin also has a M.S. in Biochemistry and Molecular Biology from Oregon Health & Science University in 2004.

Zhang S, Long H, Yang YL, Wang Y, Hsieh D, Li W, Stoppler H, Au A, Xu Z, Jablons D, You L, Inhibition of CK2α down-regulates Notch1 signaling in lung cancer cells. J Cell Mol Med. (accepted)

Yeh CC, Malhotra D, Yang YL, Xu Y, Fan Y, Li H, Mann M, MEK1-Induced Physiological Hypertrophy Inhibits Chronic Post-Myocardial Infarction Remodeling in Mice, J. Cell Biochem. 114 (2013), pp. 47-55

Yang YL, G.A. Buck and G. Widmer, Cell sorting-assisted microarray profiling of host cell response to Cryptosporidium parvum infection, Infect. Immun. 78 (2009), pp. 1040-8

Yang YL, M.G. Serrano, A.S. Sheoran, P.A. Manque, G.A. Buck and G. Widmer, Over-expression and localization of a host protein on the membrane of Cryptosporidium parvum infected epithelial cells, Mol. Biochem. Parasitol.168 (2009), pp. 95-101

G. Widmer, YL Yang and R. Bonilla et al., Preferential infection of dividing cells by Cryptosporidium parvum, Parasitology 133 (2006), pp. 131-138.

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